As a child, Li suffered from an eye disease that was supposedly caused by an overconsumption of peppercorn seeds.Li Shiz

LSZ suffered from eye disease as a child due to overconsumption of peppercorn seeds. His grandfather was a doctor, and his father encouraged him to seek a position but failed the civil service exam thrice. He became a physician and cured the Prince of Chu's son, becoming an official. Later, he worked at the Imperial Medical Institute in Beijing but left after a year to return to being a doctor.